DEET vs. Natural Bug Repellent: What the Research Says

DEET is the ingredient most people think of first when they think "bug repellent." It's also the one most people would rather avoid putting on their skin if there's a real alternative. So does natural actually work, or is that just what we tell ourselves?


close up of spray being misted on a person's arm with sun filtering

What DEET Actually Does

DEET doesn't kill insects. According to the EPA, it works by interfering with an insect's ability to detect the carbon dioxide and body odors that lead them to a person in the first place — essentially making you harder to find. It's been studied more than any other repellent ingredient on the market, and in controlled testing it has outperformed most alternatives on raw protection time.

Where Natural Repellents Hold Their Own

The research here is more interesting than most people expect. A recent study published in the journal ACS Omega found that patchouli oil, formulated correctly, protected against mosquitoes just as effectively as DEET. Clove bud oil has also performed exceptionally well in comparative testing against mosquito species — in one study, clove required a far smaller dose than patchouli to achieve the same repellent effect. Lemon eucalyptus oil has shown similarly strong results and is the only plant-based repellent the CDC recommends as comparable to low-concentration DEET.

Where Natural Repellents Fall Short

The honest caveat: results across natural repellents are inconsistent. Not every essential oil performs well, and even the ones that do tend to break down faster than DEET, meaning shorter protection windows and more frequent reapplication. A well-formulated blend using multiple effective botanicals together tends to outperform any single natural ingredient alone.

The Real Tradeoff

This isn't really a question of "does natural work." Some of it clearly does, and the research increasingly backs that up. The real tradeoff is protection duration and reapplication frequency versus what you're willing to put on your skin for hours at a time. For most everyday outdoor use — yard work, a hike, an evening on the porch — a well-formulated natural repellent holds up. For high-risk exposure to disease-carrying mosquitoes in endemic regions, DEET's longer track record still matters.

What's In Buzz Off

Buzz Off is built on lemon eucalyptus and citronella, layered with cedarwood, lavender, and peppermint — ingredients chosen because the research on each of them actually holds up.

The Bottom Line

DEET works. It's also a synthetic chemical you're putting on your skin for hours at a time, and there's a well-formulated alternative that doesn't require that tradeoff. That's reason enough to choose differently.

References

New Research Found a Natural Mosquito Repellent That Works as Well as DEET. Outside Online. https://www.outsideonline.com/health/wellness/natural-mosquito-repellent/

Comparative Efficacy of Insect Repellents against Mosquito Bites. New England Journal of Medicine. https://www.nejm.org/doi/full/10.1056/NEJMoa011699

Disclaimer: Luna Lou products are handmade from natural ingredients and are not intended to diagnose, treat, cure, or prevent any disease. Statements about ingredient benefits are based on publicly available research and traditional use, and are provided for educational purposes only — they are not a substitute for professional medical advice. Always patch test new products before full use, and discontinue use if irritation occurs. If you are pregnant, nursing, managing a medical condition, or taking medication, consult a healthcare provider before use. Keep out of reach of children and pets unless a product is specifically labeled for that use.

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